Public registration and reporting of clinical trials is essential to minimize publication bias and increase the efficiency of medical research. ClinicalTrials.gov, one of the largest and most successful trial registration initiatives to date, provides an online searchable database of clinical studies of human participants conducted around the world.
Discover proposed solutions from leading experts in meta-research from featured presentations.
As the scientific enterprise has grown in size and diversity, we need empirical evidence on the research process to test and apply interventions that make it more efficient and its results more reliable. Meta-research is an evolving scientific discipline that aims to evaluate and improve research practices. It includes thematic areas of methods, reporting, reproducibility, evaluation, and incentives (how to do, report, verify, correct, and reward science). Much work is already done in this growing field, but efforts to-date are fragmented. We provide a map of ongoing efforts and discuss plans for connecting the multiple meta-research efforts across science worldwide.
The language and conceptual framework of “research reproducibility” are nonstandard and unsettled across the sciences. In this Perspective, we review an array of explicit and implicit definitions of reproducibility and related terminology, and discuss how to avoid potential misunderstandings when these terms are used as a surrogate for “truth.”
News: Nature NewsMore Details
The Netherlands has launched what researchers say is the world’s first national fund dedicated to replication studies: a pot of €3 million (US$3.3 million) over the next 3 years for Dutch scientists to test whether they can reproduce important research results in social and medical sciences.
News: Retraction WatchMore Details
If you’ve searched recently for retracted articles in PubMed — the U.S. National Library of Medicine’s database of scientific abstracts — you may have noticed something new.
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Recently, I was asked to review a Randomized Controlled Trial concerning an antidepressant. Among my comments, I requested the authors provide individual data allowing for a re-analysis. Kindly, the authors answered me that my comment was weird and they’ve never received such a request.
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Winston Lin , Donald P. Green Methods
- Journal Title: PS: Political Science and Politics
- Publication Date: 2016
- Issue #: 03
- Page #: 495 - 499